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Osteoporosis

Older, Thinner Women Risking Hip Fracture?

Thin may be in but it is not without its risks to older women.

A study of 3,683 women published this month in the Archives of Internal Medicine has found that weight loss after age 50 raises the risk of hip fractures, a leading cause of injury and death among the elderly. The risk is particularly pronounced for middle-aged women who are already thin.

Researchers from the National Institute on Aging and the National Center for Health Statistics examined data from a long-term health study involving residents of two Iowa counties and East Boston, Mass.

They found that a weight loss after age 50 of more than 10 percent was associated with the risk of hip fractures after age 67, while a 10 percent gain appeared to provide modest protection against such injuries. The risk of hip fractures was highest among women who were thin at age 50.

Women who lost weight in middle age, a time when people tend to gain excess pounds, were more likely to be cigarette smokers or never to have smoked. They also were more likely to have two or more medical conditions, such as diabetes, and were less likely to drink alcohol than women who maintained or gained weight between middle and old age.

The reasons that weight loss increases the risk of hip fractures remain unclear. It may contribute to a loss of bone density, presage an illness or increase the risk of falls, the chief cause of hip fractures, the authors speculate.

Researchers also found that a weight gain of at least 10 pounds between ages 40 and 60 appeared to increase bone density and reduce the risk of fractures. Other studies have found that a weight gain after age 25 was associated with a reduced risk of a broken hip.

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